The Wilcoxon rank sum test was performed to assess the differences between groups for the nonnormally distributed data. The t test was applied to normally distributed data. The immune cell infiltration level was determined using cell type identification via the estimating relative subsets of RNA transcripts (CIBERSORT) algorithm.
24 (link) The estimation of stromal and immune cells in malignant tumour tissues was performed using the expression data (ESTIMATE) algorithm to calculate TME‐related parameters.
25 (link) The chi‐square test was used for statistical analysis of the enumeration data. Correlation analysis was performed via Spearman's test. All the above operations were implemented with R software 4.2.1 and GraphPad Prism 9.0.0.
24 (link) The estimation of stromal and immune cells in malignant tumour tissues was performed using the expression data (ESTIMATE) algorithm to calculate TME‐related parameters.
25 (link) The chi‐square test was used for statistical analysis of the enumeration data. Correlation analysis was performed via Spearman's test. All the above operations were implemented with R software 4.2.1 and GraphPad Prism 9.0.0.
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