Baseline Metabolic Measurements in Fasting State

Blood was drawn between 8 and 10 a.m. while participants were in the fasting state. For the current study, baseline biochemical measurements used for analysis were performed the same day. HbA_1c was measured in EDTA-anticoagulated blood on a Cobas Integra 800 CTS analyser (Roche, The Netherlands) with a NGSP (National Glycohemoglobin Standardized Program) certified turbidimetric immunoassay. Blood glucose was measured with a hexokinase method. Serum concentrations of creatinine and lipids (total-, HDL- and LDL-cholesterol, and triacylglycerol were measured on a Roche Modular P chemistry analyser (Roche, Basel, Switzerland) [22 (link)]. Estimated (e) GFR was calculated using the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formula [26 (link)].

Free full text: Click here

Boersma H.E., van Waateringe R.P., van der Klauw M.M., Graaff R., Paterson A.D., Smit A.J, & Wolffenbuttel B.H. (2021). Skin autofluorescence predicts new cardiovascular disease and mortality in people with type 2 diabetes. BMC Endocrine Disorders, 21, 14.

Publication 2021

Cobas Integra 800 CTS analyser Roche Modular P chemistry analyser

Blood Blood glucose Chronic kidney disease Creatinine Edta Glycohemoglobin Hexokinase Ldl cholesterol Lipids Serum Triacylglycerol Turbidimetric immunoassay

Corresponding Organization :

Other organizations : University Medical Center Groningen, University of Groningen, Hospital for Sick Children

Top 5 similar protocols

Variable analysis

independent variables

Not explicitly mentioned

dependent variables

HbA1c
Blood glucose
Serum creatinine
Serum total cholesterol
Serum HDL cholesterol
Serum LDL cholesterol
Serum triacylglycerol
Estimated glomerular filtration rate (eGFR)

control variables

Participants were in the fasting state
Blood was drawn between 8 and 10 a.m.
Baseline biochemical measurements were performed the same day

controls

No positive or negative controls were explicitly mentioned in the protocol.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!