Clinical effectiveness was compared between the two groups according to the levels of blood glucose. The effectiveness was defined as stabilization of fasting and postprandial blood glucose levels to the normal range without complications. Effective blood glucose control was defined as blood glucose levels close to the normal range without severe complications. Ineffectiveness was defined as blood glucose levels that were still high[7 (link),8 (link)]. BMD for lumbar vertebra of L1-4 and hip was measured by dual-energy X-ray absorptiometry (Horizon DXA system, Manufacturer: Hologic, Inc., USA, Model: Discovery A) before and after the treatment. Bone metabolic markers were compared between the two groups. Levels of N-terminal midfragment of osteocalcin, β-isomerized C-terminal telopeptides and 25-hydroxyvitamin in the blood were measured by Infinite F50 ELISA reader. The incidence of complications was observed in the duration of medication.
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Assessing Glycemic Control and Bone Health
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Other organizations : Third Hospital of Hebei Medical University, Hebei Medical University, Cangzhou Central Hospital
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Variable analysis
independent variables
- Treatment of the two groups
- Stabilization of fasting and postprandial blood glucose levels to the normal range without complications
- Blood glucose levels close to the normal range without severe complications
- Blood glucose levels that were still high
- BMD for lumbar vertebra of L1-4 and hip measured by dual-energy X-ray absorptiometry
- Levels of N-terminal midfragment of osteocalcin, β-isomerized C-terminal telopeptides and 25-hydroxyvitamin in the blood measured by Infinite F50 ELISA reader
- Incidence of complications during the duration of medication
- Levels of blood glucose
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