We used VDW files to obtain data on comorbidities and procedures from inpatient and ambulatory healthcare encounters using ICD-9 codes, lab test results, as well as ambulatory pharmacy databases and site-specific diabetes mellitus and cancer registries.
Prevalent HF was defined by any hospitalization or ambulatory HF diagnosis during the 5 years before the index date. During the 5 years before cohort entry and throughout the follow-up period, we also assessed patient records for diagnoses of acute myocardial infarction, unstable angina, coronary artery revascularization, stroke or transient ischemic attack, cerebrovascular disease, other thromboembolism, atrial fibrillation or flutter, ventricular fibrillation or tachycardia, mitral or aortic valvular heart disease, peripheral arterial disease, rheumatic heart disease, receipt of a pacemaker, receipt of cardiac resynchronization therapy, receipt of an implantable cardioverter defibrillator, dyslipidemia, hypertension, diabetes mellitus, hospitalized bleed, diagnosed dementia, diagnosed depression, chronic lung disease, chronic liver disease, mechanical fall, and systemic cancer using relevant ICD-9 codes and current procedural terminology codes that have been previously described.21 (link)At baseline and during the follow-up period, ambulatory systolic and diastolic blood pressure measurements were identified from VDW vital sign files, whereas information on serum low-density lipoprotien and high-density lipoprotein cholesterol measurements and blood hemoglobin levels were ascertained from site ambulatory lab databases.