Eligible patients provided a written informed consent prior to study participation. Data were collected as follows: baseline characteristics, laboratory results, and radiographic findings. Baseline characteristics included age, sex, etiology of cirrhosis, comorbid diseases, and the Child-Pugh score for cirrhosis. Laboratory tests in the study were platelet count, serum creatinine, prothrombin time, liver function test, AFP, and PIVKA-II. All samples were tested for AFP and PIVKA-II by using a test kit (µTASWako i30; FUJIFILM Wako Pure Chemical Corporation). Radiographic findings were numbers of liver mass, largest mass size (cm), and portal vein invasion. HCC was diagnosed by either confirmation by pathological findings or radiographic findings of arterial hypervascularity followed by venous and/or delayed phase or washout of contrast (17 (link)).
HCC Risk Profiling Protocol
Eligible patients provided a written informed consent prior to study participation. Data were collected as follows: baseline characteristics, laboratory results, and radiographic findings. Baseline characteristics included age, sex, etiology of cirrhosis, comorbid diseases, and the Child-Pugh score for cirrhosis. Laboratory tests in the study were platelet count, serum creatinine, prothrombin time, liver function test, AFP, and PIVKA-II. All samples were tested for AFP and PIVKA-II by using a test kit (µTASWako i30; FUJIFILM Wako Pure Chemical Corporation). Radiographic findings were numbers of liver mass, largest mass size (cm), and portal vein invasion. HCC was diagnosed by either confirmation by pathological findings or radiographic findings of arterial hypervascularity followed by venous and/or delayed phase or washout of contrast (17 (link)).
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Corresponding Organization :
Other organizations : Khon Kaen University
Variable analysis
- None explicitly mentioned
- HCC diagnosis
- Platelet count
- Serum creatinine
- Prothrombin time
- Liver function test
- PIVKA-II
- Number of liver masses
- Largest mass size
- Portal vein invasion
- Patients 18 years or over with a high risk for HCC
- Exclusion criteria: pregnancy, obstructive jaundice, vitamin K or warfarin administration, and presence of extrahepatic malignancy
- None specified
- None specified
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