Molecular Docking Analysis of Wogonin

The main compounds of wogonin and key protein targets were analyzed by molecular docking using the AutoDockTools 1.5.7 software^{52 (link),53}. The 3D structures of wogonin were obtained from the TCMSP database. The 3D structures of key protein targets were obtained from the RCSB Protein Data Bank (RCSB PDB) database^{54 (link)} (https://www.rcsb.org/). The figures of the active binding site were generated with the PyMOL 2.2.0 software (https://pymol.org/2/).

Free full text: Click here

Wang X., Wang Y., Chen J., Wang Q., Liu Z., Yin Y., Yang T., Shen T, & Sa Y. (2024). On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation. Scientific Reports, 14, 10114.

Publication 2024

Corresponding Organization :

Other organizations : First People's Hospital of Yunnan Province, Kunming University of Science and Technology

Top 5 similar protocols

Variable analysis

independent variables

The 3D structures of wogonin obtained from the TCMSP database.
The 3D structures of key protein targets obtained from the RCSB Protein Data Bank (RCSB PDB) database.

dependent variables

The main compounds of wogonin and key protein targets analyzed by molecular docking using the AutoDockTools 1.5.7 software.

control variables

The figures of the active binding site generated with the PyMOL 2.2.0 software.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!