Magnetic resonance imaging was performed at the UCSD Radiology Imaging Laboratory on a General Electric 1.5T EXCITE HD scanner with an 8-channel phased-array head coil. Image acquisitions included a conventional 3-plane localizer, GE calibration scan, two T1-weighted 3D structural scans (TE = 3.8ms, TR=10.7ms, TI = 1sec, flip angle= 8 deg, bandwidth=15.63 kHz, FOV=25.6 cm, matrix=192×192, slice thickness=1.0mm), and five diffusion-weighted (DW) sequences. Diffusion data were acquired using single-shot echo-planar imaging with isotropic 2.5 mm voxels (matrix size=96×96, FOV=24 cm, 47 axial slices, slice thickness=2.5 mm), covering the entire cerebrum and brainstem without gaps. Three volume series were acquired with 51 diffusion gradient directions using b-value of 600 mm2/s (TE/TR 68.4/10,900), 800 mm2/s (TE/TR 72.3/11,700), and 1,000 (TE/TR 75.6/12,300) mm2/s, each with an additional b=0 volume. For use in nonlinear B0 distortion correction, two additional series were acquired with opposite phase encoding polarity.
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Multimodal MRI Acquisition Protocol
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Corresponding Organization :
Other organizations : University of California, San Diego
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Variable analysis
independent variables
- Magnetic field strength (1.5T)
- T1-weighted 3D structural scan parameters (TE, TR, TI, flip angle, bandwidth, FOV, matrix, slice thickness)
- Diffusion-weighted imaging parameters (voxel size, matrix size, FOV, slice thickness, number of slices, b-values)
- General Electric EXCITE HD 1.5T scanner
- 8-channel phased-array head coil
- Conventional 3-plane localizer
- GE calibration scan
- Phase encoding polarity for B0 distortion correction
- Positive control: Not specified.
- Negative control: Not specified.
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