Systolic Blood Pressure and Kidney Biomarkers

Systolic blood pressure (SBP) was measured biweekly by tail-cuff (XBP1000 system Kent Scientific, Torrington, CT) (Cheng et al., 2009 (link)). Plasma creatinine was assayed using the DetectX® Serum Creatinine kit (Arbor assays, Ann Arbor, MI)(Kim, Jiang, et al., 2019 (link)) and plasma activin-A by a Quantikine ELISA kit (R&D) (Kim, Puranik, et al., 2021 (link)).

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Kim S.R., Jiang K., Chen X., Puranik A.S., Zhu X.Y., Lerman A., Tchkonia T., Kirkland J.L, & Lerman L.O. (2022). Selective kidney targeting increases the efficacy of mesenchymal stromal/stem cells for alleviation of murine stenotic-kidney senescence and damage. Journal of tissue engineering and regenerative medicine, 16(6), 550-558.

Publication 2022

XBP1000 system DetectX® Serum Creatinine kit Quantikine ELISA kit

Activin a Assays Creatinine Elisa Plasma Serum Systolic blood pressure Tail

Corresponding Organization : Mayo Clinic

Other organizations : Pusan National University Yangsan Hospital, University of Maryland, Baltimore, Second Xiangya Hospital of Central South University, Central South University, Mayo Clinic in Florida

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Systolic blood pressure (SBP)
Plasma creatinine
Plasma activin-A

control variables

None explicitly mentioned

controls

Positive control: Not specified
Negative control: Not specified

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