Sobetirome and d6-sobetirome were synthesized as previously described.40 (link), 41 (link) Anandamide (AEA, #90050), PF-3845 (#13279), and URB-937 (#10674) were purchased from Cayman. Arachidonic acid was purchased from Sigma (#23401). d11-Arachidonic acid was purchased from Avanti (#861810E). Fatty-acid free BSA was from Alfa Aesar (#64682). Solvents were HPLC grade from Fisher.