The glutamate scans were conducted using the PRESS sequence58 (link),59 (link) (TR=3000 ms, TE=30 ms, number of average=128, scan time=384 sec). A variable pulse power and optimized relaxation delays (VAPOR) technique60 (link) was used in both sequences to achieve water suppression.
High-resolution 3T MRI Acquisition of GABA and Glutamate
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Corresponding Organization :
Other organizations : Brown University, Providence College
Protocol cited in 1 other protocol
Variable analysis
- Magnetic field strength (3T)
- MRI scanner model (Siemens)
- Head matrix coil (32-channel)
- MRI sequences (MPRAGE, MEGA-PRESS, PRESS)
- T1-weighted anatomical brain structure images
- GABA concentration
- Glutamate concentration
- Voxel size (1×1×1 mm^3)
- Slice gap (0 mm)
- TR (MPRAGE: 2530 ms, MEGA-PRESS: 1500 ms, PRESS: 3000 ms)
- TE (MPRAGE: 1.64 ms, MEGA-PRESS: 68 ms, PRESS: 30 ms)
- Flip angle (MPRAGE: 7 degrees)
- FoV (MPRAGE: 256 mm)
- Matrix size (MPRAGE: 256×256)
- Bandwidth (MPRAGE: 651 Hz/pixel)
- Number of averages (MEGA-PRESS: 256, PRESS: 128)
- Scan time (MEGA-PRESS: 774 sec, PRESS: 384 sec)
- Water suppression technique (VAPOR)
- None specified
- None specified
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