As the EGJ is a difficult location for endoscopic treatment, we performed EMRC. The EMR procedures were as follows: the periphery of the lesion was marked with the tip of a snare, approximately 2 mm away from the lesion; diluted epinephrine (1:100,000) was injected into the submucosa; the lesion was drawn into the cap by suction, and the snare was closed snugly; the snared lesion was then released from the cap and resected (18 (link),19 (link)). Larger lesions required removal in multiple pieces (i.e., piecemeal EMR).
The ESD procedures were as follows: the periphery of the lesion was marked with a dual knife (KD-650L; Olympus Optical Co., Ltd., Tokyo, Japan), at least 5 mm away from the lesion, except on the oral side, where the marking was placed 1 cm from the squamocolumnar junction (SCJ) or tumor border (20 (link)); diluted epinephrine (1:100,000) was injected into the submucosa along the presumed cutting line; the mucosa surrounding the lesion was circumferentially cut with a dual knife (KD-650L) or an IT knife (KD-610L; Olympus Optical Co., Ltd.); and submucosal dissection of the connective tissue of the submucosa under the lesion was performed (21 (link)).
The ESD procedures were as follows: the periphery of the lesion was marked with a dual knife (KD-650L; Olympus Optical Co., Ltd., Tokyo, Japan), at least 5 mm away from the lesion, except on the oral side, where the marking was placed 1 cm from the squamocolumnar junction (SCJ) or tumor border (20 (link)); diluted epinephrine (1:100,000) was injected into the submucosa along the presumed cutting line; the mucosa surrounding the lesion was circumferentially cut with a dual knife (KD-650L) or an IT knife (KD-610L; Olympus Optical Co., Ltd.); and submucosal dissection of the connective tissue of the submucosa under the lesion was performed (21 (link)).
