The cardiac function of the mice was measured using echocardiography as described previously (23 (link)). Serial Doppler echocardiography was performed using the Vevo® 3100 ultrasound system with a 40-MHz high-frequency ultrasonic probe (Fujifilm VisualSonics, Toronto, ON, Canada). Left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic volume (LVEDV), and left ventricular end-systolic volume (LVESV) were measured. Fractional shortening (FS) was calculated as (LVEDD − LVESD)/LVEDD×100%, and left ventricular ejection fraction (LVEF) was calculated as (LVEDV − LVESV)/LVEDV ×100%.
Protocol detail
Echocardiographic Evaluation of Cardiac Function
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Cardiac
Diastolic
Doppler echocardiography
Echocardiography
Left ventricular
Mice
Systolic
Ultrasonic
Ultrasound
Ventricular ejection fraction
Corresponding Organization : People's Hospital of Xinjiang Uygur Autonomous Region
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Variable analysis
independent variables
- None explicitly mentioned
- Left ventricular end-diastolic diameter (LVEDD)
- Left ventricular end-systolic diameter (LVESD)
- Left ventricular end-diastolic volume (LVEDV)
- Left ventricular end-systolic volume (LVESV)
- Fractional shortening (FS)
- Left ventricular ejection fraction (LVEF)
- None explicitly mentioned
- Positive control: Not mentioned
- Negative control: Not mentioned
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