Protocol detail

FDG-PET Image Acquisition Protocol

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The image acquisition methods were same as previous studies^{20 (link),21}. Patients received fasting at least 4 h and then administered a standardized dose of 3.5 MBq 18-fluorodeoxyglucose (FDG) per kilogram body weight. After FDG injection, patients were kept in a lying position for 60 min prior to image acquisition. FDG-uptake parameters were evaluated using Advantage Workstation 4.6 software program the PET VCAR (GE Healthcare, Chalfont, UK). SUVmax was calculated automatically using a standard formula [maximum activity in region of interest ÷ (injected dose × body weight)].

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Matoba T., Minohara K., Kawakita D., Takano G., Oguri K., Murashima A., Nakai K., Iwaki S., Tsuge H., Tanaka N., Imaizumi S., Hojo W., Matsumura A., Tsukamoto K., Esaki S, & Iwasaki S. (2022). Impact of tumor burden on survival in patients with recurrent or metastatic head and neck cancer treated with immune checkpoint inhibitors. Scientific Reports, 12, 14319.

Publication 2022

Advantage Workstation 4.6 PET VCAR

Body weight Fluorodeoxyglucose Patients

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Variable analysis

independent variables

Standardized dose of 3.5 MBq 18-fluorodeoxyglucose (FDG) per kilogram body weight

dependent variables

FDG-uptake parameters evaluated using Advantage Workstation 4.6 software program the PET VCAR (GE Healthcare, Chalfont, UK)
SUVmax calculated automatically using a standard formula [maximum activity in region of interest ÷ (injected dose × body weight)]

control variables

Patients received fasting at least 4 h prior to FDG administration
Patients were kept in a lying position for 60 min prior to image acquisition

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