According to the PROCESS guidelines[10 (link)], a retrospective analysis was performed based on a single-center prospective case series. From May 2016 to June 2020, 11 patients were preoperatively diagnosed with colonic hepatic curl carcinoma with duodenal invasion at Panzhihua Central Hospital (Panzhihua, China). Before the operation, the hospital's gastrointestinal surgery specialists, internal medicine specialists, pathologists, radiologists, and imaging experts participated in the evaluation of the patient. The patients had undergone right semicolon carcinoma radical resection and duodenal-jejunal Roux-EN-Y anastomosis in the General Surgery Department of our hospital. None of them received neoadjuvant chemotherapy intervention prior to surgery. Surgeon Pei-Gen Liu, deputy chief physician, has completed laparotomy and minimally invasive laparoscopic surgery for more than 500 cases of CRC. He has rich experience in combined viscerectomy for locally advanced CRC and a profound understanding of membrane anatomy. He is quite accomplished in protecting patients’ sexual function and urination function when performing rectal cancer surgery. The surgeries were performed with the full advice and assistance of a multidisciplinary team. This study was approved by the ethics committee of Panzhihua Central Hospital (No. 20160001).
The following information of the patients was collected in detail: demographic aspects of the patients, American Society of Anesthesiologists (ASA) scores, duration of surgery, intraoperative blood loss, perioperative complications, pathological staging, and calculated overall survival and disease-free survival (DFS). Surgical risk was classified according to the ASA classification. Complications were classified according to the Clavien-Dindo classification[11 (link)]. The histopathological staging was recorded according to the tumor, nodes, metastases classification (American Joint Committee on Cancer 8th Edition for Cancer Staging).
Postoperatively, all patients were reevaluated by an oncologist to determine whether adjuvant therapy would be used. Five patients were in fair condition and underwent adjuvant chemotherapy (CAPOX, 12 wk), another two patients were not eligible for chemotherapy due to their cachexia, and four elderly patients in their 70 s gave up chemotherapy due to their elderly family members.