Structural MRI images were used to define the model for the volume conductor and the solution space for MEG source localization analysis. Images were acquired with a General Electric 1.5 Tesla using an eight-channel head coil. The imaging protocol consisted of: 3D T1-weighted high-resolution images using a Fast-Spoiled Gradient Echo sequence [TR/TE/TI=11.2/4.2/450 ms; flip-angle= 12°; FoV= 250 mm; acquisition matrix= 256 × 256; slice thickness=1 mm]. Structural images were used to reconstruct each person´s cortical surface with FreeSurfer software. Inner skull surface was used for a boundary element model of the volume conductor in the forward calculations. The solution space was approximated by ∼5000 free-rotation dipoles along the gray-white matter surface in the cortex, with spacing between dipole locations ∼7 mm (Kovacevic et al., 2012 (link)).
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MRI-based MEG Source Localization Protocol
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Corresponding Organization :
Other organizations : San Diego State University, University of Minho, Universidade de Santiago de Compostela, Universidad Complutense de Madrid, Centre for Biomedical Network Research on Rare Diseases, University of California, San Diego
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- Structural MRI images used to define the model for the volume conductor and the solution space for MEG source localization analysis
- Images acquired with a General Electric 1.5 Tesla using an eight-channel head coil
- Imaging protocol: 3D T1-weighted high-resolution images using a Fast-Spoiled Gradient Echo sequence [TR/TE/TI=11.2/4.2/450 ms; flip-angle= 12°; FoV= 250 mm; acquisition matrix= 256 × 256; slice thickness=1 mm]
- Structural images used to reconstruct each person´s cortical surface with FreeSurfer software
- Inner skull surface used for a boundary element model of the volume conductor in the forward calculations
- Solution space approximated by ∼5000 free-rotation dipoles along the gray-white matter surface in the cortex, with spacing between dipole locations ∼7 mm
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