The calcium phosphate cement (BIOCERA-VET®, TheraVet, Gosselies, Belgium) is a bioactive resorbable bone substitute with osteoconductive properties. The cement was provided in an easy-to-use dual-chambered syringe pre-filled with a powder (composed of 78 wt% (weight%) α-tricalcium phosphate (TCP), 10 wt% anhydrous dicalcium phosphate (DCPA) (CaHPO4), 10 wt% CDA, 2 wt% hydroxypropylmethylcellulose (HPMC)), and a liquid phase (5 wt% Na2HPO4 aqueous solution (liquid/powder ratio = 0.5 mL·g−1) and a 0.5 wt% Na2HPO4 aqueous solution (liquid/powder ratio = 0.45 mL·g−1)). After mixing, a final volume of 8 mL of cement was obtained. A 7G luer-lock cannula and an injection device were provided to perform the injection of the cement.
The isothermic crystallization of the cement is initiated by the reconstitution, with a setting time of 8 min and a complete hardening time of 24 h, that give rise to calcium-deficient apatite. The harden cement is characterized by a compressive strength of 13± MPa, a porosity of 63 ± 3% and a permeability of 10−8 m·s−1.
The isothermic crystallization of the cement is initiated by the reconstitution, with a setting time of 8 min and a complete hardening time of 24 h, that give rise to calcium-deficient apatite. The harden cement is characterized by a compressive strength of 13± MPa, a porosity of 63 ± 3% and a permeability of 10−8 m·s−1.
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