Vascular Reactivity Pharmacological Assay

N-ω-Nitro-L-arginine methyl ester (L-NAME), phenylephrine hydrochloride, tetraethylammonium (TEA), glibenclamide, 4-aminopyridine (4-AP), 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ), indomethacin, atropine, propranolol, sodium chloride (NaCl), potassium chloride (KCl), sodium bicarbonate (NaHCO₃), magnesium sulfate (MgSO₄), calcium chloride (CaCl₂), potassium dihydrogen phosphate (KH₂PO₄), and glucose were all purchased from Sigma–Aldrich, Inc. (St. Louis, MO, USA).

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Mariano L.N., da Silva R.D., Niero R., Cechinel Filho V., da Silva-Santos J.E, & de Souza P. (2024). Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu, in Hypertensive Rats. Plants, 13(4), 528.

Publication 2024

N-ω-Nitro-L-arginine methyl ester (L-NAME), phenylephrine hydrochloride glibenclamide indomethacin propranolol sodium bicarbonate (NaHCO3), magnesium sulfate (MgSO4), calcium chloride (CaCl2), potassium dihydrogen phosphate (KH2PO4), glucose

Corresponding Organization : Universidade do Vale do Itajaí

Other organizations : Universidade Federal de Santa Catarina

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Variable analysis

independent variables

N-ω-Nitro-L-arginine methyl ester (L-NAME)
Phenylephrine hydrochloride
Tetraethylammonium (TEA)
Glibenclamide
4-aminopyridine (4-AP)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ)
Indomethacin
Atropine
Propranolol

dependent variables

Not explicitly mentioned

control variables

Sodium chloride (NaCl)
Potassium chloride (KCl)
Sodium bicarbonate (NaHCO3)
Magnesium sulfate (MgSO4)
Calcium chloride (CaCl2)
Potassium dihydrogen phosphate (KH2PO4)
Glucose

positive controls

Not specified

negative controls

Not specified

Annotations

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