Survival Analysis of Conventional MPNSTs

Survival analysis was performed using the Cox proportional-hazards model as implemented in the R package survival (version 2.30; ref. 93 ). Significance was assessed by the likelihood ratio test using a cutoff for a statistical significance of 0.05. We considered only MPNSTs with conventional histology for survival analysis. The proportional-hazards assumption was tested using the cox.zph function from the R package survival (93 ).

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Cortes-Ciriano I., Steele C.D., Piculell K., Al-Ibraheemi A., Eulo V., Bui M.M., Chatzipli A., Dickson B.C., Borcherding D.C., Feber A., Galor A., Hart J., Jones K.B., Jordan J.T., Kim R.H., Lindsay D., Miller C., Nishida Y., Proszek P.Z., Serrano J., Sundby R.T., Szymanski J.J., Ullrich N.J., Viskochil D., Wang X., Snuderl M., Park P.J., Flanagan A.M., Hirbe A.C., Pillay N, & Miller D.T. (2023). Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA. Cancer Discovery, 13(3), 654-671.

Publication 2023

Mpnsts

Corresponding Organization : Boston Children's Hospital

Other organizations : European Bioinformatics Institute, London Cancer, University College London, University of Alabama at Birmingham, Moffitt Cancer Center, Harvard University, University of Toronto, Mount Sinai Hospital, Washington University in St. Louis, Royal Marsden NHS Foundation Trust, Institute of Cancer Research, Wellcome Centre for Human Genetics, University of Oxford, Lifespan, Rhode Island Hospital, Huntsman Cancer Institute, University of Utah, Massachusetts General Hospital, Center for Neuro-Oncology, Princess Margaret Cancer Centre, Sinai Health System, Ontario Institute for Cancer Research, Hospital for Sick Children, SickKids Foundation, Royal National Orthopaedic Hospital NHS Trust, Nagoya University Hospital, NYU Langone Health, National Cancer Institute, National Institutes of Health, Center for Cancer Research

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Variable analysis

independent variables

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