SPSS 9.0 statistical software (IBM Corporation, Armonk, NY, USA) was used for all statistical analyses. Statistics were calculated using two-way ANOVA with the Bonferroni correction. IC50 values and the half-lie values (t1/2 values) were calculated using Origin software (Origin 6.1; OriginLab Corporation, Northampton, MA, USA). The *P < 0.05 being statistically significant between groups. The heat-map of the qPCR results were obtained according to the methods by Zhou et al. (41 (link)) and Yin et al. (42 (link)).
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