This retrospective, multi-center cohort study was conducted on women who underwent IVF/ICSI cycles and achieved live births from January 2014 to October 2019 in three study centers among different provinces in China, including International Peace Maternity and Child Health Hospital (Shanghai), Ningbo Women and Children’s Hospital (Zhejiang Province), Suzhou Municipal Hospital (Jiangsu Province). The study was approved by the research ethics board of each center and written informed consent forms (ICFs) were obtained from all the participants before inclusion.
Subjects were identified from the database in three centers from January 2014 to October 2019 using the following inclusion and exclusion criteria. The inclusion criteria were set as follows: 1) female participants aged between 20 and 45 years, 2) participants with serum AMH measurement within 12 months before undergoing IVF/ICSI cycles. The participants were excluded if they met the following criteria: 1) participants who underwent pre-implantation genetic testing (PGT), 2) participants using donor semen or donor oocyte, 3) mixed transfers with embryos retrieved from different oocyte retrieval cycles, 4) women with severe chronic diseases, 5) women for whom main data were missing or who were lost to follow-up. The participants were categorized into three groups according to the <25th(low), 25th to 75th(average), and >75th(high) percentile of serum AMH concentration (0.01-1.76, 1.76-5.41, 5.41-25.00ng/ml). The subgroup analysis was conducted based on the number of live births.
Subjects were identified from the database in three centers from January 2014 to October 2019 using the following inclusion and exclusion criteria. The inclusion criteria were set as follows: 1) female participants aged between 20 and 45 years, 2) participants with serum AMH measurement within 12 months before undergoing IVF/ICSI cycles. The participants were excluded if they met the following criteria: 1) participants who underwent pre-implantation genetic testing (PGT), 2) participants using donor semen or donor oocyte, 3) mixed transfers with embryos retrieved from different oocyte retrieval cycles, 4) women with severe chronic diseases, 5) women for whom main data were missing or who were lost to follow-up. The participants were categorized into three groups according to the <25th(low), 25th to 75th(average), and >75th(high) percentile of serum AMH concentration (0.01-1.76, 1.76-5.41, 5.41-25.00ng/ml). The subgroup analysis was conducted based on the number of live births.
Free full text: Click here
