Cardiac Magnetic Resonance Imaging Protocol

A short stack of cine images was obtained using a 24-channel spine matrix coil, 6-channel body array coil (both Siemens), and steady-state free precession sequences, as described previously.^{32 (link)} In brief, all images were ECG-gated and taken during end-expiratory breath-hold. Typical steady-state free precession sequence measures were: slice thickness, 8 mm; gap, 2 mm; retrospective gating, 1.5 ms; repetition time (TR), 46 ms; flip angle 50º; field of view, 400 mm; and matrix size, 256 in frequency encode direction. When necessary, prospective gating was used in atrial fibrillation. Images were analyzed with manually drawn LV endocardial and epicardial contours in cvi42 (Circle Cardiovascular Imaging), as described previously.^{33 (link)} The validation of CMR-derived pressure–volume loops from CMR and blood pressure is described separately in the Expanded Methods in the Supplemental Material.

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Watson W.D., Green P.G., Lewis A.J., Arvidsson P., De Maria G.L., Arheden H., Heiberg E., Clarke W.T., Rodgers C.T., Valkovič L., Neubauer S., Herring N, & Rider O.J. (2023). Retained Metabolic Flexibility of the Failing Human Heart. Circulation, 148(2), 109-123.

Publication 2023

24-channel spine matrix coil cvi42

Atrial fibrillation Blood pressure Body Cardiovascular Endocardial Expiratory Pressure Spine

Corresponding Organization : John Radcliffe Hospital

Other organizations : University of Cambridge, University of Oxford, Lund University, Skåne University Hospital, Oxford University Hospitals NHS Trust, Wellcome Centre for Integrative Neuroimaging, Slovak Academy of Sciences, Institute of Measurement Science of the Slovak Academy of Sciences

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

LV endocardial and epicardial contours

control variables

Slice thickness (8 mm)
Gap (2 mm)
Retrospective gating (1.5 ms)
Repetition time (TR, 46 ms)
Flip angle (50°)
Field of view (400 mm)
Matrix size (256 in frequency encode direction)
Prospective gating for atrial fibrillation

positive controls

None explicitly mentioned

negative controls

None explicitly mentioned

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