For the first two options, we searched the database using disorder keywords such as “depression”, “depressive disorder”, “major depressive disorder”, “treatment-resistant depression”, “mania”, “bipolar disorder”, and “bipolar depression”, entered individually. For the third option, we searched using names of psychotropic drugs and other treatments, such as “olanzapine”, “risperidone”, “cognitive behaviour therapy”, “electroconvulsive therapy”, repetitive transcranial magnetic stimulation, and deep brain stimulation, again entered individually. Two authors (NV, RJ) independently searched the CTRI database using these strategies, after which a final list of studies satisfying the eligibility criteria was made by removing duplicates. We excluded studies involving interventions related to Ayurveda, Unani, and other alternative systems of medicine because the results of such studies tend to be published in journals and other destinations that might not have been accessible to us in our literature search. We also excluded studies that were not conducted primarily in patients with the disorders listed above.
Observational and Interventional Studies on Mood Disorders
For the first two options, we searched the database using disorder keywords such as “depression”, “depressive disorder”, “major depressive disorder”, “treatment-resistant depression”, “mania”, “bipolar disorder”, and “bipolar depression”, entered individually. For the third option, we searched using names of psychotropic drugs and other treatments, such as “olanzapine”, “risperidone”, “cognitive behaviour therapy”, “electroconvulsive therapy”, repetitive transcranial magnetic stimulation, and deep brain stimulation, again entered individually. Two authors (NV, RJ) independently searched the CTRI database using these strategies, after which a final list of studies satisfying the eligibility criteria was made by removing duplicates. We excluded studies involving interventions related to Ayurveda, Unani, and other alternative systems of medicine because the results of such studies tend to be published in journals and other destinations that might not have been accessible to us in our literature search. We also excluded studies that were not conducted primarily in patients with the disorders listed above.
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Corresponding Organization : Jawaharlal Institute of Post Graduate Medical Education and Research
Other organizations : ESIC Hospital, National Institute of Mental Health and Neurosciences, Kasturba Medical College, Manipal, Manipal Academy of Higher Education
Variable analysis
- Psychotropic drugs (e.g., olanzapine, risperidone)
- Lifestyle modification
- Psycho-educational treatments
- Behavioral treatments
- Cognitive behavior therapy
- Electroconvulsive therapy
- Repetitive transcranial magnetic stimulation
- Deep brain stimulation
- Mood disorders (e.g., depression, depressive disorder, major depressive disorder, treatment-resistant depression, mania, bipolar disorder, bipolar depression)
- Not explicitly mentioned
- Not specified
- Not specified
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