Protocol detail

Comprehensive Stroke Risk Assessment

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In this study, clinical data were collected from the enrolled patients, including demographics (age and sex); vascular risk factors (hypertension, diabetes mellitus, and ischemic heart disease); baseline blood pressure [systolic blood pressure (SBP) and diastolic blood pressure (DBP)]; Trial of Org 10 172 in Acute Stroke Treatment (TOAST) [large-artery atherosclerosis, cardioembolism, small-vessel occlusion, acute stroke of other determined etiology, stroke of undetermined etiology]; stroke severity (SS) [defined as mild stroke according to the National Institutes of Health Stroke Scale (NIHSS) scores of ≤ 8, moderate-to-severe stroke according to NIHSS scores of ≥9; all assessments completed on admission]; magnetic resonance imaging (MRI) features [stroke distribution (SD; anterior circulation, posterior circulation, and anterior/posterior circulation), side of hemisphere (SOH; left, right, and bilateral), number of stroke lesions (NOSs; single and multiple stroke lesions), site of stroke lesions (SOSs; cortical, cortico-subcortical, subcortical, brainstem, and cerebellum)]; laboratory tests [total cholesterol, triglycerides, low-density lipoprotein (LDL), fasting blood glucose (FBG), homocysteine (HCY), uric acid (UA), fibrinogen (FIB), myoglobin (MB), C-reactive protein (CRP), D-dimer brain natriuretic peptide (BNP), HBALC, neuron-specific enolase (NSE), and S-100β levels], treatment regimen [intravenous thrombolysis, arterial thrombolysis, antiplatelet, anticoagulation, statin, and proton pump inhibitor therapy (PPI)]; and stroke comorbidities [dysphagia and stroke-associated pneumonia (SAP)].

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Wang K., Gu L., Liu W., Xu C., Yin C., Liu H., Rong L., Li W, & Wei X. (2023). The predictors of death within 1 year in acute ischemic stroke patients based on machine learning. Frontiers in Neurology, 14, 1092534.

Publication 2023

Acute stroke Arterial Atherosclerosis Blood glucose Blood pressure Brain natriuretic peptide Brainstem C reactive protein Cerebellum Cholesterol Cortical D dimer Diabetes mellitus Diastolic blood pressure Dysphagia Fibrinogen Homocysteine Hypertension Ischemic heart disease Low density lipoprotein Myoglobin Neuron specific enolase Occlusion Patients Pneumonia Proton pump inhibitor Statin Stroke Systolic blood pressure Therapy Thrombolysis Treatment regimen Triglycerides Uric acid Vessel

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Variable analysis

independent variables

Treatment regimen [intravenous thrombolysis, arterial thrombolysis, antiplatelet, anticoagulation, statin, and proton pump inhibitor therapy (PPI)]

dependent variables

Demographics (age and sex)
Vascular risk factors (hypertension, diabetes mellitus, and ischemic heart disease)
Baseline blood pressure [systolic blood pressure (SBP) and diastolic blood pressure (DBP)]
Trial of Org 10 172 in Acute Stroke Treatment (TOAST) [large-artery atherosclerosis, cardioembolism, small-vessel occlusion, acute stroke of other determined etiology, stroke of undetermined etiology]
Stroke severity (SS) [defined as mild stroke according to the National Institutes of Health Stroke Scale (NIHSS) scores of ≤ 8, moderate-to-severe stroke according to NIHSS scores of ≥9; all assessments completed on admission]
Magnetic resonance imaging (MRI) features [stroke distribution (SD; anterior circulation, posterior circulation, and anterior/posterior circulation), side of hemisphere (SOH; left, right, and bilateral), number of stroke lesions (NOSs; single and multiple stroke lesions), site of stroke lesions (SOSs; cortical, cortico-subcortical, subcortical, brainstem, and cerebellum)]
Laboratory tests [total cholesterol, triglycerides, low-density lipoprotein (LDL), fasting blood glucose (FBG), homocysteine (HCY), uric acid (UA), fibrinogen (FIB), myoglobin (MB), C-reactive protein (CRP), D-dimer brain natriuretic peptide (BNP), HBALC, neuron-specific enolase (NSE), and S-100β levels]
Stroke comorbidities [dysphagia and stroke-associated pneumonia (SAP)]

control variables

Independent variables not explicitly mentioned.
Dependent variables not explicitly mentioned.
Control variables not explicitly mentioned.

Annotations

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