MRI Acquisition Protocol for Brain Imaging

All eligible participants were offered a high-resolution brain MRI acquired on a study-dedicated 1.5-T system (Signa Twinspeed, General Electric Medical Systems). The same imaging protocol was used in the 2002–2006 and 2007–2011 examinations, described elsewhere (21 (link), 22 (link)), and included the following sequences: 3D spoiled-gradient recalled T1-weighted, proton density/T2-weighted fast spin-echo, fluid-attenuated inversion recovery (FLAIR) and T2*-weighted gradient-echo type echoplanar (GRE-EPI). All images were acquired to give full brain coverage with slices angled parallel to the anterior commissure–posterior commissure line in order to give reproducible image views in the oblique-axial plane.

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van Sloten T.T., Sigurdsson S., van Buchem M.A., Phillips C.L., Jonsson P.V., Ding J., Schram M.T., Harris T.B., Gudnason V, & Launer L.J. (2015). Cerebral small vessel disease is associated with a higher incidence of depressive symptoms in a general elderly population: the AGES-Reykjavik Study. The American journal of psychiatry, 172(6), 570-578.

Publication 2015

Signa Twinspeed

Brain Echo Electric Examinations Inversion Proton

Corresponding Organization :

Other organizations : Icelandic Heart Association, Leiden University Medical Center, National Institutes of Health, National Institute on Aging, Reykjavík University, National University Hospital of Iceland, University of Iceland, Maastricht University Medical Centre

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Variable analysis

independent variables

High-resolution brain MRI acquired on a study-dedicated 1.5-T system (Signa Twinspeed, General Electric Medical Systems)

dependent variables

Not explicitly mentioned

control variables

The same imaging protocol was used in the 2002–2006 and 2007–2011 examinations
Images were acquired to give full brain coverage with slices angled parallel to the anterior commissure–posterior commissure line in order to give reproducible image views in the oblique-axial plane

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