Synthesis of Zinc-Curcuminoid-THC Complex

A ratio of 25:75 of THC:curcuminoid extract was created by weighing out relative amounts of THC and curcumin on a molar basis each and mixing them together to form a uniform powder (the ligand). A 2-mole amount (as based on curcumin) of ligand was added to a 1-mole amount of zinc chloride. Methanol was added to solvate the mixture and it was stirred at room temperature for 4 h. Complexation of the zinc to the curcuminoids and THC occurred during this time with an observed color change from orange to deep red. The solution containing complexed curcuminoids and THC to zinc was dried to a powder by roto-evaporation and termed TurmiZn.