Phototherapy-Induced Erythema Measurement

The MED was defined as the lowest dose of UVR (millijoules per centimeter square) causing a visually perceptible erythema at 24 h after UVR exposure as previously described (29 (link)). Erythemal intensity was also measured using a spectrophotometer (CM600d; Konica Minolta Sensing Europe, Gothenburg, Sweden) to provide hemoglobin index readings. These readings were performed at 24 and 72 h after UVR exposure. Additionally, hemoglobin index readings were taken at sites exposed to 3× MED UVR at 24, 48, and 72 h.

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Kendall A.C., Pilkington S.M., Murphy S.A., Del Carratore F., Sunarwidhi A.L., Kiezel-Tsugunova M., Urquhart P., Watson R.E., Breitling R., Rhodes L.E, & Nicolaou A. (2019). Dynamics of the human skin mediator lipidome in response to dietary ω-3 fatty acid supplementation. The FASEB Journal, 33(11), 13014-13027.

Publication 2019

CM600d

Erythemal Hemoglobin

Corresponding Organization : University of Manchester

Other organizations : National Health Service, Salford Royal NHS Foundation Trust

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Variable analysis

independent variables

Ultraviolet radiation (UVR) exposure

dependent variables

Minimal Erythema Dose (MED) of UVR
Erythemal intensity measured by spectrophotometer (hemoglobin index readings) at 24 and 72 hours after UVR exposure
Hemoglobin index readings at sites exposed to 3× MED UVR at 24, 48, and 72 hours

control variables

Not explicitly mentioned

controls

Positive control: Not mentioned
Negative control: Not mentioned

Annotations

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