Genome-wide Methylation Profiling Protocol

27 samples were used, with genome-wide methylation profiling from Illumina HumanMethylation450 BeadChip platform (34 (link)). Probe to gene conversion was done the same way as for TCGA HCC methylation data.
All the available clinical information for the confirmation cohorts is listed in Supplementary Table S1. These cohorts were used to test the Support Vector machine (SVM) machine-learning models.

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Chaudhary K., Poirion O.B., Lu L, & Garmire L.X. (2017). Deep Learning based multi-omics integration robustly predicts survival in liver cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 24(6), 1248-1259.

Publication 2017

HumanMethylation450 BeadChip platform

Gene conversion Methylation

Corresponding Organization : University of Hawaii System

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Variable analysis

independent variables

Genome-wide methylation profiling

dependent variables

Methylation levels

control variables

27 samples
Illumina HumanMethylation450 BeadChip platform
Probe to gene conversion done the same way as for TCGA HCC methylation data
Available clinical information for the confirmation cohorts listed in Supplementary Table S1

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