In the UK Biobank, more than 133,000 participants underwent an enhanced ophthalmic assessment between 2009 and 2010 at 6 assessment centres, including ophthalmic imaging.[17 ] The right eye was imaged first. Single-field colour fundus photographs (45° field-of-view, centred to include both optic disc and macula) and macular OCT scans were captured using a digital Topcon-1000 integrated ophthalmic camera (Topcon 3D OCT1000 Mark II, Topcon Corp., Tokyo, Japan). Ophthalmic examination for 8,623 EPIC-Norfolk participants was performed between 2004 and 2011. Fundus photography was acquired using a TRC-NW6S non-mydriatic retinal camera and IMAGEnet Telemedicine System (Topcon Corporation, Tokyo, Japan) with a 10 megapixel Nikon D80 camera (Nikon corporation, Tokyo, Japan).[16 (link)]