Participants were asked to identify their race by self-report using the National Eye Institute inclusion/enrollment system describing ethnicity and race (http://orwh.od.nih.gov/pubs/outreach.pdf [pages 120–121]). Information regarding a family history of glaucoma (biological mother, father, sibling, aunt, uncle, and grandparent) was also obtained. All participants were recruited from the glaucoma clinics and ophthalmic practices at each of the three recruiting sites, by advertisement and community presentations, and by referral from other ophthalmologists and optometrists in the community.
The ocular testing performed in ADAGES has been described elsewhere.14 (link) In brief, participants underwent a comprehensive ophthalmic examination, including annual review of medical history, best-corrected visual acuity, slit-lamp biomicroscopy, IOP measurement, dilated funduscopic examination, pachymetry, simultaneous stereoscopic optic disc photography, and standard automated perimetry VF testing with the 24–2 Swedish interactive threshold algorithm (Carl Zeiss Meditec, Inc., Dublin, California, USA). VFs were repeated every 6 months and optic disc photographs were performed every 12 months.