Core Proteome Analysis of Nocardia Subspecies

A total of 218 complete proteome sequences of the 6 Nocardia subspecies (i.e., Nocardia farcinica, Nocardia cyriacigeorgica, Nocardia abscessus, Nocardia otitidiscaviarum, Nocardia brasiliensis, and Nocardia nova) were obtained from the NCBI (National Center for Biotechnology Information) database on May 1st, 2022. The Bacterial Pan Genome Analysis (BPGA) tool v1.3, which utilizes USEARCH to cluster proteins with a sequence identity threshold of 0.5, was employed to identify core proteins (27 (link), 28 (link)).

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Zhu F., Tan C., Li C., Ma S., Wen H., Yang H., Rao M., Zhang P., Peng W., Cui Y., Chen J, & Pan P. (2023). Design of a multi-epitope vaccine against six Nocardia species based on reverse vaccinology combined with immunoinformatics. Frontiers in Immunology, 14, 1100188.

Publication 2023

A 218 Bacterial genome Nocardia Nocardia abscessus Nocardia brasiliensis Nocardia cyriacigeorgica Nocardia farcinica Nocardia nova Nocardia otitidiscaviarum Proteins Proteins sequence Proteome

Corresponding Organization : Central South University

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Variable analysis

independent variables

Not explicitly mentioned

dependent variables

Not explicitly mentioned

control variables

The BPGA tool v1.3 was used to identify core proteins with a sequence identity threshold of 0.5, indicating that the sequence identity threshold is a control variable.

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