Modeling Metastatic Lung and Breast Cancer
Corresponding Organization :
Other organizations : Purdue University System, Case Western Reserve University, Cleveland Clinic Lerner College of Medicine
Protocol cited in 6 other protocols
Variable analysis
- Parental (that is, scrambled shRNA) and FGFR1-manipulated D2.A1 cells
- BGJ-398 (ChemieTek, Indianapolis, IN, USA) or PF-573271 (PF271; Pfizer Pharmaceuticals, New York, NY, USA) at 50 mg/kg
- Cdh1 reporter 4T1 cells (1 × 10^4 cells)
- Luciferase-expressing NME cells (1 to 2 × 10^6 cells)
- Pulmonary tumors in mice bearing D2.A1 cells
- Circulating 4T1 tumor cells isolated from the inferior vena cava
- Tumor growth of luciferase-expressing NME cells
- 5-week-old female BALB/C mice (The Jackson Laboratory, Bar Harbor, ME, USA)
- 4-week-old BALB/c mice
- 5-week-old female nu/nu mice
- None specified
- Parental (that is, scrambled shRNA) D2.A1 cells
Annotations
Based on most similar protocols
As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.
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