Illumina Sequencing of Wild Strain DNA
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Corresponding Organization : Northwestern University
Other organizations : Seoul National University, New York University, University of Massachusetts Chan Medical School, Institut de Biologie Valrose, Wageningen University & Research, Biodiversity Research Center, Academia Sinica, Howard Hughes Medical Institute, University of California, Los Angeles, Institut de Biologie de l'École Normale Supérieure, Inserm
Protocol cited in 8 other protocols
Variable analysis
- Amount of animal tissue used for DNA isolation (100-300 µl of packed animals)
- DNA concentration
- DNA fragment size (300-500 bp)
- Use of the Blood and Tissue DNA isolation kit (QIAGEN)
- Addition of RNase following initial lysis
- Use of the Qubit dsDNA Broad Range Assay Kit and Qubit dsDNA High Sensitivity Assay Kit for DNA concentration determination
- Use of the Illumina Nextera Sample Prep Kit and Nextera Index Kit for library generation and indexing
- Size selection by electrophoresis on a 2% agarose gel
- Purification using the QIAGEN MinElute Kit
- Sequencing platform (Illumina HiSeq 2500)
- Additional data incorporated from two previous studies
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