4D Flow MRI of Thoracic Aorta in TAVR Patients

The TAVR patients and controls underwent cardiac and respiratory-gated sagittal 4D flow MRI of the thoracic aorta at 3.0 Tesla (Philips). Standard transmit and receive cardiac coils were used for 4D flow measurements. 4D flow MRI sequence parameters were as follows: spatiotemporal resolution: 2.5 × 2.5 × 2.5 mm³, temporal resolution: ± 40ms (24 timeframes); TE/TR/FA = 2.1 ms/3.4 ms/8°; VENC: 150–250 cm/s; k-t PCA acceleration factor: 8. Two-al (2D) phase-contrast MRI scout measurements at the level of the sinotubular junction were conducted to estimate the optimal velocity encoding to minimise velocity aliasing. SAVR patients were included as part of a previously published study and underwent 4D flow MRI at 1.5 Tesla with scan parameters as earlier described [14 (link)].

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Farag E.S., Vendrik J., van Ooij P., Poortvliet Q.L., van Kesteren F., Wollersheim L.W., Kaya A., Driessen A.H., Piek J.J., Koch K.T., Baan J., Planken R.N., Kluin J., Nederveen A.J, & de Mol B.A. (2018). Transcatheter aortic valve replacement alters ascending aortic blood flow and wall shear stress patterns: A 4D flow MRI comparison with age-matched, elderly controls. European Radiology, 29(3), 1444-1451.

Publication 2018

3.0 Tesla

Acceleration Cardiac Mri scan Ms ms Patients Phase contrast Respiratory Scan mri Sinotubular junction Thoracic aorta

Corresponding Organization : University of Amsterdam

Other organizations : Academic Medical Center

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Variable analysis

independent variables

MRI field strength (3.0 Tesla for TAVR patients and controls, 1.5 Tesla for SAVR patients)

dependent variables

Cardiac and respiratory-gated sagittal 4D flow MRI of the thoracic aorta

control variables

Transmit and receive cardiac coils used for 4D flow measurements
Spatiotemporal resolution: 2.5 × 2.5 × 2.5 mm^3
Temporal resolution: ± 40ms (24 timeframes)
TE/TR/FA = 2.1 ms/3.4 ms/8°
VENC: 150–250 cm/s
K-t PCA acceleration factor: 8
2D phase-contrast MRI scout measurements at the level of the sinotubular junction to estimate the optimal velocity encoding to minimise velocity aliasing

controls

2D phase-contrast MRI scout measurements at the level of the sinotubular junction were conducted to estimate the optimal velocity encoding to minimise velocity aliasing.

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