18F-PSMA-1007 PET/CT Imaging Protocol

The patients were not specially prepped on the day of ¹⁸F-PSMA-1007 PET/CT scanning. A Biograph mCT-64 scanner (Siemens, Germany) was used. The scanning was performed about 180 min (14 (link)) after intravenous injection of ¹⁸F-PSMA-1007. The localizer was positioned with a scout head view. Low-dose CT (120 kV/110 mA) was then performed for anatomical localization and attenuation correction. Single-bed emission scans were obtained in three-dimensional mode (acquisition time, 3 min). Reconstruction of data was done using an ordered subset expectation maximization iterative reconstruction algorithm (three iterations, 21 subsets). The emission data were corrected for random, scatter, and decay.

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Dang J., Yao Y., Li Y., Tan X., Ye Z., Zhao Y., Qing S., Kou Y., Jiang X., Lu H., Chen S., Zhao M, & Cheng Z. (2023). An exploratory study of unexplained concentration of 18F-PSMA-1007 in the bladder for prostate cancer PET/CT imaging. Frontiers in Medicine, 10, 1238333.

Publication 2023

Biograph mCT-64 scanner

Head Patients Pet ct Psma 1007 Reconstruction Scans

Corresponding Organization : University of Electronic Science and Technology of China

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Variable analysis

independent variables

Time between intravenous injection of 18F-PSMA-1007 and PET/CT scanning (approximately 180 min)

dependent variables

PET/CT images

control variables

No special patient preparation on the day of 18F-PSMA-1007 PET/CT scanning
Use of Biograph mCT-64 scanner (Siemens, Germany)
Low-dose CT (120 kV/110 mA) for anatomical localization and attenuation correction
Emission scans in three-dimensional mode (acquisition time, 3 min)
Reconstruction of data using ordered subset expectation maximization iterative reconstruction algorithm (three iterations, 21 subsets)
Correction of emission data for random, scatter, and decay

controls

No positive or negative controls were explicitly mentioned in the given information.

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