U0126 (MEK1/2 inhibitor) and BAY11-7082 (NF-κB inhibitor) were dissolved in dimethyl sulfoxide (DMSO) (final concentration <1%) as stock solutions. The stock solution was diluted with phosphate-buffered saline (PBS).
All rats were randomly divided into five groups of six rats each; group 1: Sham group, rats were given sham operation and intragastrically administered the same volume of 0.9% NaCl solution, n = 6; group 2: Endo group, rats with autologous uterine tissue transplantation were intragastrically administered the same volume of 0.9% NaCl solution, n = 6; group 3: Endo+DMSO group, EMs rats, which were intraperitoneally injected with vehicle treatment (5% DMSO in 300 μL sterile PBS), n = 6; group 4: Endo+U0126 group, EMs rats, which were intraperitoneally injected with U0126 (20 mg/kg) in vehicle, n = 6; and group 5: Endo+BAY11-7082 group, EMs rats, which were intraperitoneally injected with BAY11-7082 (20 mg/kg) in vehicle, n = 6; all treatments were continued for 4 weeks.
All rats were randomly divided into five groups of six rats each; group 1: Sham group, rats were given sham operation and intragastrically administered the same volume of 0.9% NaCl solution, n = 6; group 2: Endo group, rats with autologous uterine tissue transplantation were intragastrically administered the same volume of 0.9% NaCl solution, n = 6; group 3: Endo+DMSO group, EMs rats, which were intraperitoneally injected with vehicle treatment (5% DMSO in 300 μL sterile PBS), n = 6; group 4: Endo+U0126 group, EMs rats, which were intraperitoneally injected with U0126 (20 mg/kg) in vehicle, n = 6; and group 5: Endo+BAY11-7082 group, EMs rats, which were intraperitoneally injected with BAY11-7082 (20 mg/kg) in vehicle, n = 6; all treatments were continued for 4 weeks.
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