An episode of candidemia was defined as the isolation of a Candida spp. from blood culture [3 (link)]. If there was more than 1 candidemia episode in the same patient, only the first episode was considered for the study.
Two blood culture sets from peripheral sites were obtained from patients with fever (≥38 °C) or clinical presentation suggestive of infection and sent off to the clinical laboratory of the Microbiology Department. The blood samples were analyzed using a BACTEC 9240 system (Becton-Dickinson Microbiology Systems, Franklin Lakes, NJ, USA) or BacT/Alert (BioMérieux SA, Marcy L’Etoile, France).
We defined septic shock using the international consensus definition for sepsis and septic shock as a subset of sepsis in which the underlying abnormalities of cellular and circulatory metabolism are profound enough to substantially increase mortality, in which vasopressor therapy is needed to elevate the mean arterial pressure ≥65 mmHg despite adequate fluid resuscitation [26 (link),27 (link)]. PMV was considered greater than 48 h [28 (link)]. RRT was considered in case of potassium derangements, acid-base disbalance, fluid overload, or pronounced azotemia [29 (link)].
Two blood culture sets from peripheral sites were obtained from patients with fever (≥38 °C) or clinical presentation suggestive of infection and sent off to the clinical laboratory of the Microbiology Department. The blood samples were analyzed using a BACTEC 9240 system (Becton-Dickinson Microbiology Systems, Franklin Lakes, NJ, USA) or BacT/Alert (BioMérieux SA, Marcy L’Etoile, France).
We defined septic shock using the international consensus definition for sepsis and septic shock as a subset of sepsis in which the underlying abnormalities of cellular and circulatory metabolism are profound enough to substantially increase mortality, in which vasopressor therapy is needed to elevate the mean arterial pressure ≥65 mmHg despite adequate fluid resuscitation [26 (link),27 (link)]. PMV was considered greater than 48 h [28 (link)]. RRT was considered in case of potassium derangements, acid-base disbalance, fluid overload, or pronounced azotemia [29 (link)].
Free full text: Click here
