The baseline interview included questions on demographics, medical history (including diabetes and cancer), usual diet, tobacco and alcohol use, height, weight, physical activity, and family history of cancer. The interview and lifestyle factors have been described previously (Tsong et al., 2007 (link); Odegaard et al., 2011a (link)) (see Text, Supplemental Digital Content 1, description of lifestyle factors). Physical activity was reported for the past year in categories of moderate activities (brisk walking, bowling, bicycling on level ground, tai chi, or chi kung), strenuous sports (jogging, bicycling on hills, squash, swimming laps, or aerobics), and vigorous work (moving heavy furniture, loading or unloading trucks, shoveling, or equivalent manual labor). For each category of activity, participants reported average time spent each week in intervals of never, ½–1 hr., 2–3 hrs., 4–6 hrs., 7–10 hrs., 11–20 hrs., 21–30 hrs., and 31 hrs. or more. Based on the frequency of physical activity in the study population, the intensity variables were dichotomized into ≥ ½ hr/week physical activity and no reported physical activity within each respective intensity. Participants were also asked to report the average time spent sitting per day for watching television and other sitting activities (i.e., reading, playing cards, and sewing) in intervals of never, less than 1 hr., 1–2 hrs., 3–4 hrs., 5–6 hrs., 7–10 hrs., and 11 hrs. or more. Time spent sitting watching television was dichotomized into ≥3 hrs/day and ≤ 2 hours/per day based on the distribution of television watching time in this sample. Other sitting was examined in categories of none, <1hr/day, 1–2 hrs/day, and ≥3 hrs/day.