Transcriptomic Analysis of Normal and Cancer Tissues
Transcriptomic data from normal tissues and cancer samples were obtained with the Affymetrix technology “Affymetrix.GeneChip. HG-U133_Plus_2.” We used data available either on the GEO Web site (http://www.ncbi.nlm.nih.gov/geo/) or from our own lung tumor series (GSE30219). The data were analyzed as described in the Supplementary Materials and Methods. Thresholds of expression for germline- and placenta-restricted genes were established as described in the Supplementary Materials and Methods.
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Rousseaux S., Debernardi A., Jacquiau B., Vitte A.L., Vesin A., Nagy-Mignotte H., Moro-Sibilot D., Brichon P.Y., Lantuejoul S., Hainaut P., Laffaire J., de Reyniès A., Beer D.G., Timsit J.F., Brambilla C., Brambilla E, & Khochbin S. (2013). Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers. Science translational medicine, 5(186), 186ra66.
Publication 2013
Cancer GenechipGenes Germline Lung tumor Normal tissuesPlacenta Transcriptomic
Corresponding Organization : Université Joseph Fourier
Other organizations :
Centre Hospitalier Universitaire de Grenoble, International Prevention Research Institute, La Ligue Contre le Cancer, University of Michigan–Ann Arbor
Data available on the GEO Web site or from the authors' own lung tumor series (GSE30219)
Thresholds of expression for germline- and placenta-restricted genes
controls
Positive controls: Not explicitly mentioned.
Negative controls: Not explicitly mentioned.
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