A 24-gauge sterile subcutaneous catheter (McKesson Medical-Surgical Inc. Richmond, VA) was inserted into the dorsal subcutaneous space between the back skin and the muscle. A single bolus of Gd (0.1 mmol/kg bodyweight, using 1:10 dilution of Multihance, Gadobenate dimeglumine injection solution, 529 mg/ml, Bracco Diagnostics, Inc. Monroe Twp, NJ) was administered between time frames 4 and 5 via the subcutaneous catheter during the dynamic contrast enhancement (DCE) MRI acquisition.