Cardiac computed tomography angiography (CCTA) imaging was performed using a 64-slice dual-source CT scanner (Siemens Medical Solutions, Malvem, PA, USA). The CCTA protocol has been described previously (13 (link),14 (link))(18 (link)). This protocol included a non-contrast CT for calculation of Agatston calcium score (19 (link)) and contrast-enhanced retrospectively-ECG gated CCTA for assessment of calcified and noncalcified coronary plaque segments. In addition, cine images were reconstructed throughout each phase of the cardiac cycle to assess ventricular function. An experienced cardiac radiologist reviewed the images to calculate the Agatston calcium score, for noncalcified or mixed coronary plaque, presence of moderate (50–69%) or severe (≥ 70%) stenosis, and for qualitative assessment of left ventricular function on a dedicated workstation (Siemens Syngo MMWP). Abnormal left ventricular systolic function was defined as an estimated left ventricular ejection fraction < 50%.
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Cardiac CT Angiography Protocol
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Abnormal left ventricular function
Calcium
Computed tomography angiography
Coronary
Ct scanner
Left ventricular function
Plaque
Radiologist
Stenosis
Systolic
Ventricular ejection fraction
Ventricular function
Corresponding Organization :
Other organizations : University of Maryland, Baltimore, Inova Health System, Massachusetts General Hospital, Harvard University
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Variable analysis
independent variables
- Independent variables not explicitly mentioned.
- Agatston calcium score
- Presence of noncalcified or mixed coronary plaque
- Presence of moderate (50–69%) or severe (≥ 70%) stenosis
- Qualitative assessment of left ventricular function
- Abnormal left ventricular systolic function (defined as an estimated left ventricular ejection fraction < 50%)
- 64-slice dual-source CT scanner (Siemens Medical Solutions, Malvern, PA, USA)
- Cardiac computed tomography angiography (CCTA) protocol described previously in references 13, 14, and 18
- Non-contrast CT for Agatston calcium score calculation
- Contrast-enhanced retrospectively-ECG gated CCTA for assessment of calcified and noncalcified coronary plaque segments
- Cine images reconstructed throughout each phase of the cardiac cycle to assess ventricular function
- Review by an experienced cardiac radiologist
- Positive control: None specified.
- Negative control: None specified.
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