All whole-brain T1- and T2-weighted MRI scans were collected on a Siemens Magnetom Prisma 3 Tesla MRI scanner using a 32-channel head coil at the University of Southern California’s Center for Image Acquisition. The 3D T1 and T2 weighted structural images were acquired using sagittal whole-brain MPRAGE sequences (T1: TR = 2,400 ms, TE = 2.22 ms, flip angle = 8°, BW = 220 Hz/Px, FoV = 256 mm, 208 slices, and 0.8 mm isotropic voxels, with a GRAPPA phase-encoding acceleration factor of 2; T2: TR = 3,200 ms, TE = 563 ms, BW = 744 Hz/Px, FoV = 256 mm, 208 slices, 0.8 mm isotropic voxels, and 3.52 ms echo spacing, with a GRAPPA phase-encoding acceleration factor of 2). The T1 sequence lasted 6 min and 38 s, and the T2 sequence lasted 5 min and 57 s. All scans were reviewed by a radiologist for incidental findings of abnormalities and all images underwent visual quality control to assess for motion and were rated on a 3-point scale of Pass, Check, Fail (Backhausen et al., 2016 (link)). All 71 included participants were rated as Pass or Check before preprocessing; four participants that were originally collected for this study, did not have usable data and were excluded from this analysis (i.e., Fail and were not included).
Free full text: Click here