Bone Gene Expression and Hip Geometry Association
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Corresponding Organization : Bar-Ilan University
Other organizations : Harvard University, Broad Institute, Erasmus MC, Erasmus University Rotterdam, University of Ioannina, University of Rochester, Sir Charles Gairdner Hospital, Augusta University, University of Pittsburgh, University of Hong Kong, California Pacific Medical Center, Boston University, Indiana University – Purdue University Indianapolis, University of Virginia, Lovisenberg Diakonale Sykehus, University of Oslo, Office of Extramural Research, MRC Epidemiology Unit, University of Bristol, Translational Research Institute, University of Queensland, University of Gothenburg, University of Maryland, Baltimore, Oregon Health & Science University, Oslo University Hospital, McGill University, Jewish General Hospital, University of California, Davis, University of Iceland, King's College London, deCODE Genetics (Iceland), NIHR Oxford Musculoskeletal Biomedical Research Centre, University of Western Australia, GlaxoSmithKline (United Kingdom), GlaxoSmithKline (United States)
Variable analysis
- Hip geometry SNPs (and their proxies)
- Transcript levels of genes in the vicinity of the identified loci
- Women undergoing bone biopsies were free from diseases other than osteoporosis or receiving medication (past or present) possibly affecting bone remodeling or representing secondary causes of osteoporosis
- No positive or negative controls were explicitly mentioned in the input protocol.
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