Fifty patients diagnosed with BECTS were recruited from the Neurology Department of the Nanjing Brain Hospital and Nanjing Children’s Hospital of China. Meanwhile, we initiated socially-oriented recruitment for the healthy control group, enrolling 24 children. All the patients were diagnosed by meeting the International League Against Epilepsy (ILAE) 2017 criteria. Moreover, all the enrolled patients were included in the study without taking antiepileptic drugs (AEDs).
The inclusion criteria for patients were: (1) conformed to the classification of epilepsy syndrome using the ILAE2017; (2) not taking any AEDs; (3) aged 6–14 years; (4) normal mental and physical development, no mental or somatic disease or neurodevelopmental delay. The exclusion criteria were: (1) the presence of implanted mental devices, including artificial pacemakers, which could create obvious noise and interfere with the MEG results; (2) evidence of intellectual disability, neurological disorders, and significant systemic organ disorders; (3) history of trauma and asphyxia during childbirth; and (4) unable to cooperate with the research process.
Of the 50 patients, one had a history of obstetric injuries, and one did not cooperate with the MRI scan. Finally, 48 children were included in the study. The Medical Ethics Committee of Nanjing Medical University, Nanjing Brain Hospital, and Nanjing Children’s Hospital Medical Ethics Committee approved the research. The parents or legal guardians of the subjects provided a signed informed consent form.
The inclusion criteria for patients were: (1) conformed to the classification of epilepsy syndrome using the ILAE2017; (2) not taking any AEDs; (3) aged 6–14 years; (4) normal mental and physical development, no mental or somatic disease or neurodevelopmental delay. The exclusion criteria were: (1) the presence of implanted mental devices, including artificial pacemakers, which could create obvious noise and interfere with the MEG results; (2) evidence of intellectual disability, neurological disorders, and significant systemic organ disorders; (3) history of trauma and asphyxia during childbirth; and (4) unable to cooperate with the research process.
Of the 50 patients, one had a history of obstetric injuries, and one did not cooperate with the MRI scan. Finally, 48 children were included in the study. The Medical Ethics Committee of Nanjing Medical University, Nanjing Brain Hospital, and Nanjing Children’s Hospital Medical Ethics Committee approved the research. The parents or legal guardians of the subjects provided a signed informed consent form.
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