Efficacy and Safety of Hiccup Treatment

(1) Clinical efficacy: Cure: the hiccup completely stopped 3 days after treatment. Remission: the attack times of hiccup were obviously reduced, which is more than 50% lower than that before treatment. Invalid: the above criteria are not met or the disease aggravates [12 (link)]. Total effective rate = (cured + relieved) cases/total cases × 100%. The patient’s median response time, the median cure time, and the one-time medication response rate were recorded. (2) Adverse reactions and recurrence: adverse reactions including fatigue (conscious fatigue and limb weakness), drowsiness (excessive daytime sleep or sleep onset), tremors (rhythmic and alternating swinging movements), and hiccup recurrence after drug discontinuation were recorded during the treatment.