MR studies were performed with 2 1.5T MR tomographs: a Magnetom Symphony (Siemens, Erlangen, Germany) and Magnetom Aera (Siemens). The MRI images were acquired before and after an intravenous (IV) contrast agent (CA) injection.
In this study, a radiomics features extraction was made on volumetric interpolated breath-hold examination (VIBE) T1-weighted SPAIR with controlled respiration used to acquire images after IV CA injection with a liver-specific CA (0.1 mL/kg of Gd-EOB-BPTA—Primovist, Bayer Schering Pharma, Berlin, Germany). The VIBE T1-W sequence was acquired with 2 different flip angles (10 and 30 degrees). A power injector (Spectris Solaris® EP MR, MEDRAD Inc., Indianola, IA, USA) was used to administrate the CA at an infusion rate of 2 mL/s, as descripted in our previous studies [26 (link),27 (link)]. Table 2 reports MR Sequence parameters.
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