Urinary Isoflavone Metabolites and Cancer Mortality

The levels of isoflavone metabolites, including daidzein (ng/mL), equol (ng/mL), genistein (ng/mL), and O-desmethylangolensin (O-DMA, ng/mL) in the urine, were obtained from the NHANES, which were measured by high-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry. Only the data in the year 2007–2010 were publicly accessible in the survey years of our study. The association between urinary isoflavone metabolite levels and cancer-related mortality was analyzed using Cox proportional hazards analysis. Meanwhile, the special weights “wtsb2yr” or “wtsa2yr” for special urine examination were employed in the Cox analysis.