Quantifying Thoracic Aortic Remodeling
Corresponding Organization : Monash University Malaysia
Other organizations : Nanyang Technological University, SEGi University, University of Nottingham Malaysia Campus
Variable analysis
- None explicitly mentioned
- Thickness of the aorta
- Media thickness (distance from the internal elastic lamina to the external lamina)
- Lumen inner diameter
- Media-to-lumen ratio (an index of aortic vascular remodelling)
- Well-fixed thoracic aortic ring specimens
- Conventional tissue processing and embedding in paraffin wax
- Thin sections (5 µm) stained with hematoxylin and eosin (H&E)
- Nikon Eclipse Ti2 microscope used to capture microscopic images (4× and 40×)
- Nikon NIS-Element AR software (Version 5.1) used to measure the variables
- No positive or negative controls were explicitly mentioned in the input protocol.
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