Eighteen-week-old MRL/lpr (n = 24) and MRL/MpJ mice (n = 24) were randomized for pharmacological treatment analysis, as previously described (25 (link)). Mice were orally administered 100 mg/kg fisetin (Tokyo Chemical Industry) (MRL/MpJ: n = 12 and MRL/lpr: n = 12) or vehicle (20% PEG 400) (MRL/MpJ: n = 12 and MRL/lpr: n = 12) five days a week for four weeks.
Free full text: Click here