Statistical analyses were accomplished using IBM SPSS Statistics 24 for Windows. The difference between the control and kindle groups was analyzed using a t-test. Two-way ANOVA was conducted to analyze the effect of seizure and telenzepine on the LTP induction. Further analysis for multiple comparisons was done using the Bonferroni posthoc test. All data were presented as mean ± SEM, with a significant P-value at the level of less than 0.05 for all tests. The percentage (%) of changes in the amplitude of PS and slope of fEPSP due to HFS was normalized in the 10-min baseline recording. The averaged response got during the last 10-min baseline recording was used as a reference, and was compared with the averaged response obtained during the 60-min post-HFS recording. A potentialize data analysis package (Science Beam, Iran) was used to determine the fEPSP or the PS magnitude, as previously described (22 (link)). Paired pulse PS index and paired-pulse index of fEPSP were driven from averaged waveforms as the pulse2/pulse1 ratio at inter-pulse intervals of 10, 20, 80, 100, and 200 ms (23 (link)24 (link)).