Multimodal Brain Structural Analysis

T1-Brain structure image was acquired by using a Siemens Magnetom Verio 3.0T scanner (Siemens, Munich, Germany). The parameters of T1-weighted 3D magnetization prepared rapid gradient echo (MPRAGE) sequences were as follows: TR = 2,300 ms, TE = 2.98 ms, matrix size = 240 × 256; flip angle of 9 degree, field of view (FOV) = 240 × 256 mm; slice thickness = 1.2 mm. Volumetric data was assessed by automated procedures, which have been described by Wolz R et al. (30 (link)). For each subject, volume and asymmetry with various brain areas as well as cortical thickness were extracted directly using FreeSurfer v6.0. Based on our previous research basis and previous literature (10 (link), 31 (link), 32 (link)), we took the volume of hippocampus, amygdala and the cortical thickness of rostral middle frontal gyrus as our target research objects.

Free full text: Click here

Li W., Yue L, & Xiao S. (2022). Subjective cognitive decline is associated with a higher risk of objective cognitive decline: A cross-sectional and longitudinal study. Frontiers in Psychiatry, 13, 950270.

Publication 2022

Magnetom Verio 3.0T scanner

Amygdala Brain Cortical Echo Frontal cortical Hippocampus

Corresponding Organization : Shanghai Jiao Tong University

Top 5 similar protocols

Variable analysis

independent variables

None explicitly mentioned

dependent variables

Volume of hippocampus
Volume of amygdala
Cortical thickness of rostral middle frontal gyrus

control variables

Magnetic resonance imaging (MRI) scanner type (Siemens Magnetom Verio 3.0T)
MRI acquisition parameters (TR = 2,300 ms, TE = 2.98 ms, matrix size = 240 × 256, flip angle of 9 degree, field of view (FOV) = 240 × 256 mm, slice thickness = 1.2 mm)
Automated volumetric data assessment procedures (as described by Wolz R et al.)
FreeSurfer v6.0 software for extracting volume, asymmetry, and cortical thickness

controls

No positive or negative controls were explicitly mentioned in the information provided.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!